O'Keeffe's Working Hands Hand Cream – Desk-Side Hand Cream for Office and Remote Work Recovery
O'Keeffe's Working Hands Hand Cream – Desk-Side Hand Cream for Office and Remote Work Recovery
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Why you'll love it
- Trusted as the #1 hand cream brand in America, reducing purchase risk
- Clinically proven to instantly boost moisture and create a protective barrier, promising visible results within days
- Hypoallergenic, unscented and non-greasy formula safe for diabetics and sensitive skin
- Backed by a 100% money-back guarantee from the manufacturer
- Convenient 2-pack of travel-size tubes for home, work, and on-the-go use
- Concentrated glycerin-based formula that absorbs quickly without leaving residue
Perfect for
- Repairing extreme dryness and cracks after hand washing throughout the day
- Overnight hand treatment applied at bedtime for deep moisture recovery
- Post-bathing hand moisturizing to lock in hydration
- Travel-ready hand care in a 3 oz TSA-compliant tube
- Daily maintenance for diabetics or those with sensitive skin prone to cracking




Product Information
Get your hands back: O’Keeffe’s Working Hands is a concentrated moisturizing cream that heals, relieves, soothes and repairs extremely cracked, dry hands; From the #1 hand cream brand in America*
Guaranteed relief for extremely dry hands: A hand cream that creates a protective layer on the skin's surface, locking in moisture and keeping even the driest skin hydrated and healthy
Hardworking skincare: O'Keeffe's Working Hands dry hand cream provides an instant moisture boost to relieve your discomfort and repair your dry skin to be full, moisturized and nourished
Recommended use: For best results, apply after hand washing, after bathing, and at bedtime - these are the most effective times for moisturizing extremely dry hands
Hypoallergenic: O'Keeffe's Working Hands is unscented, non-greasy and safe for people with diabetes; Our 3 ounce tube is an ideal hand cream travel size so you can be comfortable on the go
O’Keeffe’s Working Hands Hand Cream is a concentrated, unscented hand cream that heals, relieves and repairs extremely dry, cracked hands. When used daily, O’Keeffe’s Working Hands Hand Cream is clinically proven to instantly boost moisture levels, help prevent further moisture loss, create a protective layer on the skin's surface that locks in moisture and keeps your skin hydrated, and make a difference you will feel within days. O’Keeffe’s offers a tube version of our moisturizing hand cream. Our tube formula offers the same results O’Keeffe’s jar users know and expect in the convenience of a tube! Whether you prefer a tube or jar, O’Keeffe’s Working Hands Hand Cream comes in both forms to provide relief. Click on the O'Keeffe's link at the top of this page to shop the O'Keeffe's Brand Store.Age Range Description: Adult
Skin Type: Dry
Number of Items: 2
Item Form: Cream
Target Use Body Part: Hands
Product Benefits: Hypoallergenic, Moisturizing, Softening
Specific Uses For Product: Dryness
Model Name: 3oz Tube
Container Type: Tube
Recommended Uses For Product: Hydrating
Global Trade Identification Number: 00722510000126
Item Type Name: O'Keeffe's - K0290001 - 2pk
Included Components: O'Keeffe's - K0290001 - 2pk
Warranty Description: 100% Money Back Guarantee: Please contact the O’Keeffe’s Company at 1-800-275-2718 for details.
Item Volume: 3 fluid ounces
Item Dimensions: 9.5 x 6.5 x 2 inches
Item Weight: 6.4 ounces
Special Ingredients: Glycerin
Material Type Free: Alcohol Free
Other Special Features of the Product: Hypoallergenic, Unscented
Scent Name: Unscented
Frequently Asked Questions
Will this hand cream absorb fast enough that I don't lose time during a busy shift?
Yes, the non-greasy formula absorbs in seconds, so you can apply it between patients, classes, or tasks without missing a beat.
Is it safe to apply this hand cream right before putting on latex or nitrile gloves?
Yes, the fast-absorbing, non-greasy formula is designed to be glove-friendly, so it will not cause gloves to slip off or degrade latex and nitrile materials.
Can I keep one tube at my desk and one in my bag for back-to-back meetings?
Yes, the 2-pack is designed exactly for that — one tube at your primary workspace and one in your travel bag, car, or locker for on-the-go use.
Will this hand cream actually repair the damage from constant hand washing at work?
Yes, O'Keeffe's is clinically proven to repair dryness and cracking from frequent hand washing, sanitizer use, and glove wear — the exact conditions found in healthcare, food service, and teaching.
Is this an appropriate hand cream to use during a long study or work-from-home session?
Yes, applying it as a quick mid-session reset gives your hands a moment of care without breaking your focus, and the unscented formula will not compete with your workspace environment.
Will the tube stay sealed in my laptop bag or work tote without leaking?
Yes, the flip-top cap is designed to stay closed under normal bag pressure, and the squeeze tube is leak-resistant for daily commute and travel use.
Is this hand cream strong enough for chefs, nurses, and teachers who wash their hands all day?
Yes, O'Keeffe's is the #1 hand cream brand in America and was developed specifically for hands damaged by constant washing, sanitizer, and glove use in demanding professions.
Does the unscented formula stay neutral in a small or shared workspace?
Yes, the completely fragrance-free formula will not compete with coffee, food, or shared office scents, making it ideal for cubicles, shared desks, and clinical environments.
Can I use this hand cream during a Zoom call without it looking or feeling greasy on camera?
Yes, the non-greasy formula absorbs fully and leaves no visible residue, so you can apply it right before a call without shiny hands showing up on camera.
Is it a good idea to keep a tube in my car for use between work stops?
Yes, the 3 oz tube is a perfect size to keep in a center console, door pocket, or glove box, and the formula holds up well across the temperature swings of a parked car.
How does this compare to a pump bottle of generic hand lotion for office use?
A pump bottle of generic lotion is mostly water and sits on the surface, while O'Keeffe's concentrated glycerin formula is clinically proven to repair cracks and lock in moisture for long-lasting relief.
Will my coworkers or patients be bothered by the smell if I apply it at work?
No, O'Keeffe's is completely unscented, so it will not produce any noticeable fragrance that could bother patients, coworkers, or customers nearby.
Does O'Keeffe's offer a guarantee if it doesn't hold up to my demanding work routine?
Yes, the manufacturer offers a 100% money-back guarantee, so you can try it on your toughest workdays with no financial risk.
How do I apply O'Keeffe's Working Hands Hand Cream for the best results?
Squeeze a small amount onto clean hands and massage into the palms, fingers, knuckles, and cuticles. Apply at bedtime, after bathing, or any time hands feel dry. For maximum repair, apply at night and allow the cream to absorb fully.
How often should I apply the hand cream each day?
For best results, apply 2 to 3 times daily, with an overnight application at bedtime recommended for deep repair of cracked, dry hands.
Can I use this hand cream on other parts of my body, like feet or elbows?
Yes, O'Keeffe's Working Hands can be used on feet, elbows, knees, and any other area of dry, cracked skin, though the formula is specifically optimized for the hand area.
Is this hand cream compatible with my blood glucose monitor or CGM sensor?
Yes, O'Keeffe's is safe for diabetic skin and will not interfere with blood glucose meter readings or continuous glucose monitor sensors when used as directed on the hands.
Will this hand cream work with cotton gloves, hand masks, or overnight treatments?
Yes, the fast-absorbing formula pairs well with cotton overnight gloves, silicone hand masks, or paraffin wax treatments to enhance deep moisturization.
What's included in the box when I order this product?
You will receive two 3 oz squeeze tubes of O'Keeffe's Working Hands Hand Cream (6 oz total) in a single retail pack, ready to use with no additional setup required.
Is this hand cream safe for people with sensitive skin or allergies?
Yes, O'Keeffe's Working Hands is hypoallergenic, unscented, alcohol-free, and dye-free, making it well-suited for sensitive skin and most allergy profiles.
What if the hand cream doesn't work for me — can I get a refund?
Yes, the manufacturer offers a 100% money-back guarantee, so you can return the product for a full refund if you are not satisfied with the results.
How is a concentrated hand cream different from a regular body lotion?
Regular body lotions are mostly water and provide only surface-level hydration, while O'Keeffe's is a concentrated glycerin-based cream clinically proven to create a protective barrier and repair extreme dryness and cracks.

