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Crest Pro-Health Advanced Toothpaste – Trusted Sensitive Teeth and Gingivitis Care for Worry-Free Family Brushing, 5.1 Oz

Crest Pro-Health Advanced Toothpaste – Trusted Sensitive Teeth and Gingivitis Care for Worry-Free Family Brushing, 5.1 Oz

Regular price $4.46 USD
Regular price $8.45 USD Sale price $4.46 USD -47%
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Why you'll love it

  • one tube delivers 8 clinically proven benefits, simplifying the oral care routine
  • patented stannous fluoride provides trusted, dentist-recommended protection
  • starts fighting plaque and protecting enamel from Day 1, not just over time
  • continues working between brushings for longer-lasting protection
  • deep clean mint flavor leaves a strong, fresh feeling after use

Perfect for

  • twice-daily brushing to prevent gingivitis and cavities
  • enamel strengthening and acid erosion defense after acidic meals or drinks
  • relief for sensitive teeth during hot/cold food consumption
  • ongoing plaque control between dental cleanings
  • breath freshening with a deep clean mint flavor


Enjoy safe and effective teeth whitening right from home designed by the #1 teeth whitening brand in America.* Recommended by dentists & thousands of happy customers.


Crest has developed the largest collection of stannous flouride toothpastes available to improve whole mouth health and provide an enjoyable brushing experience.


Round out our oral care routine with the specialized mouthwash solution that's best for you.









Product Information
Deep cleaning formula

Healthier gums by helping prevent gingivitis

Stronger teeth by strengthening enamel

Cleans beyond what you can see

Continues to work between brushings
Starting from Day 1, Advance to Healthier Gums and Stronger Teeth* with Crest Pro-Health Advanced. This toothpaste contains ActivClean Crystals for advanced stain prevention. Crest Pro-Health Advanced Deep Clean Mint Toothpaste, like all Crest Pro-health toothpastes, cleans beyond what you can see and continues to work between brushings. It is made with patented stannous fluoride and provides clinically proven protection. It provides 8 advanced benefits in 1, including: protection against cavities, plaque and gingivitis, acid erosion† and tooth sensitivity for whole mouth health * vs. ordinary toothpaste with continued use. Starts fighting plaque and protecting enamel from Day 1. †Acid erosion effects: acids in everyday food can soften and thin enamel, leaving teeth less white, weaker and sensitive

Items Details


Features & Specs
Item Form: Gel, Paste
Product Benefits: Deep Clean
Active Ingredients: glycerin,silica
Package Type Name: Tube

Frequently Asked Questions

Is stannous fluoride safe for daily use?

Yes. Stannous fluoride is a trusted, dentist-recommended active ingredient that has been used in oral care for decades and is considered safe for twice-daily brushing in adults.

Can my whole family use this toothpaste without worry?

Yes. It is designed for adult family members and delivers broad cavity, plaque, and gingivitis protection, making it a safe, single-tube option for a shared family bathroom when used as directed.

Does this toothpaste contain ingredients I should be cautious about?

It is formulated with patented stannous fluoride and ActivClean Crystals. As with any fluoride toothpaste, it should not be swallowed, and children under 6 should use it only with adult supervision.

Is it safe for people with sensitive teeth or early gum issues?

Yes. It is specifically designed for people prone to sensitivity and gingivitis, and it is gentle enough for daily use while still providing strong enamel and gum protection.

Will it irritate my mouth if I have early gingivitis?

No. It is formulated to help reverse early signs of gingivitis with continued use, and most users with early gum issues tolerate it well for twice-daily brushing.

Is this a safer choice than whitening toothpastes with harsh abrasives?

Yes. ActivClean Crystals provide advanced stain prevention through a gentler action, so you get a cleaner, brighter feel without the high abrasion levels of some whitening pastes.

How does it compare to a basic cavity-protection toothpaste in terms of safety?

It is comparable in safety and goes further by adding sensitivity relief, gingivitis defense, and enamel strengthening, all in one dentist-recommended formula.

Is it safer for enamel than a charcoal or baking soda toothpaste?

Generally, yes. Charcoal and some baking soda pastes can be abrasive over time, while this formula focuses on strengthening enamel and defending against acid erosion.

How does it compare to a prescription toothpaste for sensitivity?

It is not a prescription product, but it uses patented stannous fluoride, which is clinically proven to relieve sensitivity, making it a strong over-the-counter alternative for many users.

I'm worried about long-term chemical exposure — is daily use really safe?

Yes. Stannous fluoride and the other active ingredients have a long safety record, and the product is designed and tested for twice-daily lifelong use as part of a normal oral care routine.

What if my gums tingle or feel sore after switching to this toothpaste?

Mild adjustment effects can occur in the first week. If irritation persists beyond that, stop use and consult your dentist to rule out any underlying sensitivity.

Is it safe if a small amount is accidentally swallowed during brushing?

Small accidental amounts are generally not a concern for adults, but it should not be swallowed intentionally, and children should always be supervised to minimize ingestion.

Does it meet dentist-recommended standards for cavity and gingivitis protection?

Yes. It is built around a patented stannous fluoride system that meets clinical standards for cavity prevention, plaque control, and gingivitis reduction.

Will it interact badly with my other dental products like mouthwash?

It works well alongside most fluoride or antimicrobial mouthwashes. For best results, avoid rinsing with water or mouthwash immediately after brushing so the fluoride can stay on your teeth longer.

Is this toothpaste approved for daily preventive use by dental professionals?

Yes. Stannous fluoride is widely recommended by dental professionals for daily preventive care, and this product is one of the most recognized implementations of that active ingredient.

What if I'm still unsure whether this is safe for my specific dental condition?

If you have a specific medical or dental condition, consult your dentist before switching. For most healthy adults, this toothpaste is considered a safe, everyday option.

How do I use Crest Pro-Health Advanced Deep Clean Mint toothpaste correctly?

Brush thoroughly at least twice a day, preferably after meals, for two minutes each time. Use about a pea-sized amount, and do not rinse with water immediately after brushing so the fluoride can stay in contact with your teeth longer.

How long should one 5.1 oz tube last with regular use?

With twice-daily brushing using a pea-sized amount, a 5.1 oz tube typically lasts one adult roughly 6 to 8 weeks, depending on how much you apply.

Can I use this toothpaste with a manual or electric toothbrush?

Yes. It works with both manual and electric toothbrushes. Pairing it with a soft-bristled brush and gentle pressure is usually the most enamel-friendly approach.

Is this toothpaste compatible with my fluoride mouthwash?

Yes. For best results, avoid rinsing with mouthwash right after brushing so the toothpaste's fluoride remains on your teeth. You can use mouthwash at a different time of day if you prefer.

Is it safe to use alongside whitening strips or other whitening products?

Yes, in most cases. Use the toothpaste for your regular twice-daily brushing and follow the whitening product's specific instructions separately, and consult your dentist if you have concerns about sensitivity.

What exactly comes in the box when I order this toothpaste?

You receive one 5.1 oz tube of Crest Pro-Health Advanced Deep Clean Mint toothpaste. No additional accessories are included, so you will need to supply your own toothbrush and floss.

Can this toothpaste cause any side effects I should know about?

Some users may experience mild temporary adjustment effects such as a slight taste change or minor gum tingling in the first week. If irritation persists, discontinue use and consult your dentist.

Is this product tested and safe for long-term daily use?

Yes. It is built around patented stannous fluoride, a long-established and dentist-recommended active ingredient, and is formulated and tested for twice-daily lifelong use in adults when used as directed.

What is the difference between this toothpaste and regular Crest Cavity Protection?

Regular Crest Cavity Protection focuses mainly on cavity prevention. Crest Pro-Health Advanced adds 7 additional benefits, including gingivitis defense, sensitivity relief, plaque control, enamel strengthening, acid erosion defense, stain prevention, and breath freshening, all in one formula.

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